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Hybrid coronary revascularization: promising, but yet to take off

机译:混合冠状动脉血运重建:有希望,但尚未起飞

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摘要

Hybrid coronary revascularization (HCR) combines arterial coronary artery bypass surgery (most commonly minimally invasive) and percutaneous coronary intervention in the treatment of a particular subset of multivessel coronary artery disease. It was first introduced in the mid-1990s, and aspired to bring together the "best of both worlds": the excellent patency rates and survival benefits associated with the durable left internal mammary artery graft to the left anterior descending artery alongside the good patency rates of drug-eluting stents, which outlive saphenous vein grafts to non-left anterior descending vessels. Although in theory this is a very attractive revascularization strategy, several years later, only one small randomized controlled trial comparing HCR with coronary artery bypass grafting has recently emerged in the medical literature, raising concerns regarding HCR's role and generalizability. In the current review, we discuss HCR's rationale, the current evidence behind it, its limitations and procedural challenges.
机译:混合冠状动脉血运重建术(HCR)结合了动脉冠状动脉搭桥术(最常见的是微创治疗)和经皮冠状动脉介入治疗,以治疗多支冠状动脉疾病的特定子集。它于1990年代中期首次引入,并希望将“两全其美”结合在一起:与持久的左乳内动脉持久移植到左前降支动脉相关的出色的通畅率和生存益处以及良好的通畅率药物洗脱支架,其比大隐静脉移植物长到非左前降支血管。尽管从理论上讲这是一种非常有吸引力的血运重建策略,但几年后,医学文献中最近才出现一项比较HCR与冠状动脉搭桥术的小型随机对照试验,引起了人们对HCR的作用和可推广性的担忧。在当前的审查中,我们讨论了HCR的基本原理,其背后的当前证据,其局限性和程序挑战。

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